SCHEMBL7108216

SCHEMBL7108216

Oc1ccc(C(CCl)c2ccc(O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.46
ESR2 Q92731 8/20 0.46
ALOX15 P16050 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
LMNA P02545 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CHRM2 P08172 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
CYP2D6 P10635 1/20 0.46
CHRM1 P11229 1/20 0.46
DRD1 P21728 1/20 0.46
TBXA2R P21731 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1595841 0.78 ESR1 (0.50) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL1596715 0.78 ESR1 (0.50) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL7623681 0.77 ESR1 (0.44) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL27504475 0.77 TAAR1 (0.60) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL6715483 0.77 TAAR1 (0.60) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL7201656 0.76 TSHR (0.46) TDP1LMNACYP3A4CYP2C9CYP1A2
SCHEMBL1268287 0.76 ESR1 (0.48) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL11239990 0.75 ESR1 (0.59) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL7040363 0.75 ESR1 (0.47) ESR1ESR2ALOX15TDP1LMNA
SCHEMBL9728549 0.75 HTR2A (0.52) TDP1TAAR1TSHRMTORRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939509-A Epoxy resin, resin composition, and resin-encapsulated semiconductor device SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-08-17 US claimed
US-5939473-A Epoxy resin, resin composition, and resin-encapsulated semiconductor device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-08-17 US claimed
EP-0739877-B1 Epoxy resin, resin composition, and resin-encapsulated semiconductor device SUMITOMO CHEMICAL CO (JP) 1999-08-04 EP claimed
EP-0739877-A2 Epoxy resin, resin composition, and resin-encapsulated semiconductor device SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-30 EP claimed
EP-0001910-B1 PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF MONSANTO COMPANY (US) 1981-09-02 EP claimed
EP-0001909-B1 PREPARATION OF 1,2-BIS(4-HYDROXYARYL)ETHANES BY ONE-STEP DEHYDROHALOGENATION-REARRANGEMENT-HYDROGENATION OF 1,1-BIS(4-HYDROXYARYL)-2-HALOETHANES, WHICH MAY BE FOLLOWED BY ACYLATION MONSANTO COMPANY (US) 1981-08-12 EP claimed
US-4189610-A Preparation of 4,4-dioxy-substituted stilbenes MONSANTO COMPANY (US) 1980-02-19 US claimed
US-4156787-A HYDROGENATION CATALYST MONSANTO COMPANY (US) 1979-05-29 US claimed
EP-0001910-A1 Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof MONSANTO COMPANY (US) 1979-05-16 EP claimed
EP-0001909-A1 Preparation of 1,2-bis(4-hydroxyaryl)ethanes by one-step dehydrohalogenation-rearrangement-hydrogenation of 1,1-bis(4-hydroxyaryl)-2-haloethanes, which may be followed by acylation MONSANTO COMPANY (US) 1979-05-16 EP claimed
JP-9012498-A None JP disclosed
JP-8301974-A None JP disclosed
JP-10017513-A None JP disclosed
EP-0869140-B1 Epoxy resin composition and resin-encapsulated semiconductor device SUMITOMO CHEMICAL CO (JP) 2003-08-13 EP disclosed
US-6190786-B1 BIS(GLYCIDYLOXY)STILBENE RESINS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-02-20 US disclosed
US-4189610-A Preparation of 4,4-dioxy-substituted stilbenes MONSANTO COMPANY (US) 1980-02-19 US disclosed
US-4156787-A HYDROGENATION CATALYST MONSANTO COMPANY (US) 1979-05-29 US disclosed
US-4156787-A HYDROGENATION CATALYST MONSANTO COMPANY (US) 1979-05-29 US disclosed
EP-0001910-A1 Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof MONSANTO COMPANY (US) 1979-05-16 EP disclosed
EP-0001909-A1 Preparation of 1,2-bis(4-hydroxyaryl)ethanes by one-step dehydrohalogenation-rearrangement-hydrogenation of 1,1-bis(4-hydroxyaryl)-2-haloethanes, which may be followed by acylation MONSANTO COMPANY (US) 1979-05-16 EP disclosed