Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108487 | 1.00 | RARB (0.38) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6972634 | 0.94 | RARB (0.39) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6977745 | 0.94 | RARB (0.39) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6901871 | 0.94 | RARB (0.39) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6901873 | 0.94 | RARB (0.39) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6972630 | 0.94 | RARB (0.39) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6977908 | 0.93 | RARB (0.38) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6977917 | 0.93 | RARB (0.38) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL7106010 | 0.93 | RARB (0.37) | RARBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL7106009 | 0.93 | RARB (0.37) | RARBRAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042302-B1 | LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 2003-09-24 | — | — | EP | disclosed |
| US-6309561-B1 | Liquid crystal compounds having a chiral fluorinated terminal portion | 3M INNOVATIVE PROPERTIES COMPANY | 2001-10-30 | — | — | US | disclosed |