Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.52 |
| ▸ | THRA | P10827 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108517 | 0.74 | PSEN1 (0.47) | PSEN1THRATHRBMEN1KMT2A | |
| SCHEMBL6885035 | 0.74 | TSHR (0.39) | THRATHRB | |
| SCHEMBL20470661 | 0.71 | PSEN1 (0.51) | PSEN1MEN1KMT2ATDP1 | |
| SCHEMBL9786771 | 0.68 | MIF (0.36) | THRATHRBMEN1KMT2A | |
| SCHEMBL9786760 | 0.68 | MEN1 (0.36) | THRATHRBMEN1KMT2A | |
| SCHEMBL13960182 | 0.67 | PSEN1 (0.44) | PSEN1THRATHRBMEN1KMT2A | |
| SCHEMBL13084628 | 0.66 | PSEN1 (0.67) | PSEN1MEN1KMT2A | |
| SCHEMBL12064790 | 0.66 | PSEN1 (0.67) | PSEN1MEN1KMT2A | |
| SCHEMBL635099 | 0.66 | PSEN1 (0.67) | PSEN1MEN1KMT2A | |
| SCHEMBL627640 | 0.66 | PSEN1 (0.67) | PSEN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041568-A | Production of (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acid and related compounds | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-08-20 | — | — | US | claimed |
| EP-1345601-A2 | USE OF 5-HYDROXY AND 5-ACYLOXY-2,3-DIHYDRO-4,6,7-TRIMETHYL-2-BENZOFURANACETIC ACIDS AND THEIR ESTERS AS AGENTS USEFUL FOR HEALING SKIN LESIONS AND STIMULANTS OF ANGIOGENESIS | Biomedica Foscama Industria Chimico-Farmaceutica S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| EP-1345601-A2 | USE OF 5-HYDROXY AND 5-ACYLOXY-2,3-DIHYDRO-4,6,7-TRIMETHYL-2-BENZOFURANACETIC ACIDS AND THEIR ESTERS AS AGENTS USEFUL FOR HEALING SKIN LESIONS AND STIMULANTS OF ANGIOGENESIS | Biomedica Foscama Industria Chimico-Farmaceutica S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002049642-A3 | USE OF 5-HYDROXY AND 5-ACYLOXY-2,3-DIHYDRO-4,6,7-TRIMETHYL-2-BENZOFURANACETIC ACIDS AND THEIR ESTERS AS AGENTS USEFUL FOR HEALING SKIN LESIONS AND STIMULANTS OF ANGIOGENESIS | FOSCAMA BIOMED CHIM FARMA (IT) | 2003-01-30 | — | — | WO | disclosed |
| WO-2002049642-A3 | USE OF 5-HYDROXY AND 5-ACYLOXY-2,3-DIHYDRO-4,6,7-TRIMETHYL-2-BENZOFURANACETIC ACIDS AND THEIR ESTERS AS AGENTS USEFUL FOR HEALING SKIN LESIONS AND STIMULANTS OF ANGIOGENESIS | FOSCAMA BIOMED CHIM FARMA (IT) | 2003-01-30 | — | — | WO | disclosed |
| WO-2002049642-A2 | USE OF 5-HYDROXY AND 5-ACYLOXY-2,3-DIHYDRO-4,6,7-TRIMETHYL-2-BENZOFURANACETIC ACIDS AND THEIR ESTERS AS AGENTS USEFUL FOR HEALING SKIN LESIONS AND STIMULANTS OF ANGIOGENESIS | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002049642-A2 | USE OF 5-HYDROXY AND 5-ACYLOXY-2,3-DIHYDRO-4,6,7-TRIMETHYL-2-BENZOFURANACETIC ACIDS AND THEIR ESTERS AS AGENTS USEFUL FOR HEALING SKIN LESIONS AND STIMULANTS OF ANGIOGENESIS | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 2002-06-27 | — | — | WO | disclosed |
| EP-0848953-A1 | 5-Hydroxy- and 5-acyloxy-2,3-dihydro-4,6,7-trimethyl-2-benzofurane-acetic acids and their esters for treating and preventing diabetic complications | Biomedica Foscama Industria Chimico-Farmaceutica S.p.A. (IT) | 1998-06-24 | — | — | EP | disclosed |
| EP-0848953-A1 | 5-Hydroxy- and 5-acyloxy-2,3-dihydro-4,6,7-trimethyl-2-benzofurane-acetic acids and their esters for treating and preventing diabetic complications | Biomedica Foscama Industria Chimico-Farmaceutica S.p.A. (IT) | 1998-06-24 | — | — | EP | disclosed |
| EP-0848953-A1 | 5-Hydroxy- and 5-acyloxy-2,3-dihydro-4,6,7-trimethyl-2-benzofurane-acetic acids and their esters for treating and preventing diabetic complications | Biomedica Foscama Industria Chimico-Farmaceutica S.p.A. (IT) | 1998-06-24 | — | — | EP | disclosed |
| CN-1034574-C | Process for preparing (RS)-2-(2,3-dihydro-5-hydroxy--4,6,7-trimethylbenzofuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, and their..... | FOSCAMA BIOMED CHIM FARMA (IT) | 1997-04-16 | — | — | CN | disclosed |
| CN-1034574-C | Process for preparing (RS)-2-(2,3-dihydro-5-hydroxy--4,6,7-trimethylbenzofuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, and their..... | FOSCAMA BIOMED CHIM FARMA (IT) | 1997-04-16 | — | — | CN | disclosed |
| US-5041568-A | Production of (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acid and related compounds | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-08-20 | — | — | US | disclosed |
| US-5041568-A | Production of (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acid and related compounds | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-08-20 | — | — | US | disclosed |
| US-4999350-A | PREVENTION OF TISSUE DAMAGE FROM FREE RADICALS AND OXIDIZING METABOLITES | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |
| US-4999350-A | PREVENTION OF TISSUE DAMAGE FROM FREE RADICALS AND OXIDIZING METABOLITES | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |
| US-4999350-A | PREVENTION OF TISSUE DAMAGE FROM FREE RADICALS AND OXIDIZING METABOLITES | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |