SCHEMBL7108692

SCHEMBL7108692

N=C(N)c1ccc(CNC(=O)[C@@H]2C[C@H]3CCCC[C@@H]3N2C(=O)[C@@H](Cc2ccccc2)NCC(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2 P00734 18/20 0.63
PROC P04070 4/20 0.52
F7 P08709 2/20 0.47
F10 P00742 1/20 0.47
PRSS1 P07477 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108693 1.00 F2 (0.63) F2PROCF7F10PRSS1
SCHEMBL7102482 0.86 F2 (0.63) F2F10
SCHEMBL7102480 0.86 F2 (0.63) F2F10
SCHEMBL7107381 0.84 F2 (0.66) F2PROCF10
SCHEMBL23794105 0.84 F2 (0.58) F2PROCF10
Hydrochloric Acid SCHEMBL9228058 0.83 F2 (0.65) F2PROCF10
SCHEMBL7104993 0.78 F2 (0.49) F2PROC
SCHEMBL7104999 0.78 F2 (0.49) F2PROC
SCHEMBL7105032 0.76 F2 (0.57) F2
SCHEMBL23793680 0.75 F2 (0.56) F2PROCF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672658-B1 Antithrombotic agents ASTRAZENECA AB (SE) 2003-09-17 EP claimed