SCHEMBL7109470

SCHEMBL7109470

CC(CC1CC=CCC1)[SiH](Cl)Cl

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1525278 0.78 KDM4E (0.41) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL18030165 0.75 KDM4E (0.39) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL12532460 0.75 KDM4E (0.39) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL6905685 0.75 KDM4E (0.36) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL27311648 0.73 KDM4E (0.40) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL6911566 0.72 KDM4E (0.35) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL6910876 0.72 KDM4E (0.35) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL9639863 0.71 KDM4E (0.32) KDM4EALDH1A1TDP1PKM
SCHEMBL13354403 0.70 KDM4E (0.37) KDM4EALDH1A1TDP1POLBPKM
SCHEMBL7173036 0.70 KDM4E (0.36) KDM4EALDH1A1TDP1POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072603-B1 Hydrosilylation of 4-vinyl-1-cyclohexene SHINETSU CHEMICAL CO (JP) 2003-10-01 EP disclosed
US-6245925-B1 REACTING 4-VINYL-1-CYCLOHEXENE WITH A HYDROGENCHLOROSILANE COMPOUND IN THE PRESENCE OF PLATINUM CATALYST, REMOVING RESIDUES AND ISOMERS, AND REACTING THE MONOSILYL COMPOUND AGAIN WITH HYDROGENCHLOROSILANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-06-12 US disclosed
EP-1072603-A2 Hydrosilylation of 4-vinyl-1-cyclohexene SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-01-31 EP disclosed