Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109627 | 1.00 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL9119896 | 0.78 | MAOB (0.55) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| (Z)-1,2-Diphenylethene SCHEMBL28173310 | 0.76 | MAOB (0.52) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL6865938 | 0.74 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL5572948 | 0.74 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL6834934 | 0.74 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL396616 | 0.74 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL3802508 | 0.74 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| SCHEMBL27745 | 0.74 | MAOB (0.50) | MAOBTRPA1ALDH1A1LMNANFE2L2 | |
| Cinnamonitrile SCHEMBL23599 | 0.74 | KDM4E (0.54) | MAOBTRPA1ALDH1A1LMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667341-B2 | Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters; anticancer agents, hemological disorders, and inherited metabolic disorders | BEACON LABORATORIES, INC. | 2003-12-23 | — | — | US | disclosed |
| US-20030171409-A1 | Novel delta dicarbonyl compounds and methods for using the same | BEACON LABORATORIES, INC, A DELAWARE CORPORATION | 2003-09-11 | — | — | US | disclosed |
| US-6562995-B1 | Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having | BEACON LABORATORIES, INC. | 2003-05-13 | — | — | US | disclosed |
| US-20020137775-A1 | Novel delta dicarbonyl compounds and methods for using the same | ERRANT GENE THERAPEUTICS, LLC | 2002-09-26 | — | — | US | disclosed |
| EP-1216986-A2 | Novel delta dicarbonyl compounds and methods for using same | Beacon Laboratories, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-1027350-A1 | AMINOMETHYL-BENZO A]QUINOLIZIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATIONS FOR NEURODEGENRATIVE DISEASES | PIERRE FABRE MEDICAMENT (FR) | 2000-08-16 | — | — | EP | disclosed |
| US-5977021-A | SUBSTRATE, HEAT SENSITIVE RECORDING LAYER, BARRIER AND RELEASE LAYER | OJI PAPER CO., LTD (JP) | 1999-11-02 | — | — | US | disclosed |
| WO-1999021856-A1 | AMINOMETHYL-BENZO[A]QUINOLIZIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATIONS FOR NEURODEGENRATIVE DISEASES | PIERRE FABRE MEDICAMENT (FR) | 1999-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171409-A1 | Novel delta dicarbonyl compounds and methods for using the same | HCCS, CPS1, ACAA2 | MAOB 3201/4885TRPA1 4700/4885ALDH1A1 937/4885 |
| US-20020137775-A1 | Novel delta dicarbonyl compounds and methods for using the same | HCCS, CPS1, ACAA2 | MAOB 3201/4885TRPA1 4700/4885ALDH1A1 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.