SCHEMBL71106

SCHEMBL71106

O=C(Oc1ccccc1)c1cc2ccccc2cc1C(=O)Oc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.69
KDM4E B2RXH2 4/20 0.69
TDP1 Q9NUW8 2/20 0.69
ALDH1A1 P00352 4/20 0.65
NPSR1 Q6W5P4 1/20 0.65
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
ALOX15 P16050 1/20 0.62
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
CYP3A4 P08684 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CHRM1 P11229 1/20 0.56
TBXA2R P21731 1/20 0.56
SLC6A2 P23975 1/20 0.56
PDE4A P27815 1/20 0.56
ADRA1A P35348 1/20 0.56
KDR P35968 1/20 0.56
SLC6A3 Q01959 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19281366 0.94 MAPT (0.62) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL347898 0.91 HSD17B10 (0.67) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL1098951 0.90 HPGD (0.67) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL11800875 0.87 IDO1 (0.65) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL12311611 0.85 MAPT (0.57) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL11774177 0.85 HSD17B10 (0.60) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL11770454 0.85 HSD17B10 (0.60) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL27566769 0.84 HSD17B10 (0.70) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL29437924 0.84 HSD17B10 (0.76) MAPTKDM4ETDP1ALDH1A1NPSR1
SCHEMBL69868 0.84 HSD17B10 (0.76) MAPTKDM4ETDP1ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885KDM4E 717/4885TDP1 3534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.