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Sugi Predict / Compounds / SCHEMBL7110783

SCHEMBL7110783

SCHEMBL7110783

CCC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1C[SiH2]CC1C(CC)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.33
▸ CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3997088 0.99 BRD4 (0.33) BRD4CREBBP
SCHEMBL3999811 0.89 BRD4 (0.32) BRD4CREBBP
SCHEMBL7198398 0.88 BRD4 (0.35) BRD4CREBBP
SCHEMBL7783132 0.88 BRD4 (0.35) BRD4CREBBP
SCHEMBL6890535 0.88 BRD4 (0.35) BRD4CREBBP
SCHEMBL7105425 0.88 BRD4 (0.31) BRD4CREBBP
SCHEMBL3818126 0.85 PDCD1 (0.31) —
SCHEMBL4001907 0.84 PDCD1 (0.30) —
SCHEMBL15668690 0.84 BRD4 (0.32) BRD4CREBBP
SCHEMBL22411214 0.84 BRD4 (0.34) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 — — EP claimed