SCHEMBL7110845

SCHEMBL7110845

C=CC(c1ccc(C)cc1)[S+]([O-])C(C=C)c1ccc(C)cc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.37
ACHE P22303 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TLR9 Q9NR96 1/20 0.31
TGM2 P21980 1/20 0.31
STAT3 P40763 1/20 0.30
CYP2A6 P11509 1/20 0.30
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30
TRPV6 Q9H1D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776592 0.77 CYP2C19 (0.35) TDP1MEN1KMT2A
SCHEMBL158242 0.72 CHRNA7 (0.42) CHRNA7ACHETDP1GAAMEN1
SCHEMBL16166848 0.70 CHRNA7 (0.41) CHRNA7ACHETDP1GAAMEN1
SCHEMBL4905102 0.68 ORAI1 (0.42) CHRNA7ACHETDP1GAAMEN1
SCHEMBL4853724 0.68 CHRNA7 (0.39) CHRNA7ACHETDP1GAAMEN1
SCHEMBL1082916 0.68 CHRNA7 (0.39) CHRNA7ACHETDP1GAAMEN1
SCHEMBL11210246 0.68 CHRNA7 (0.39) CHRNA7ACHETDP1GAAMEN1
SCHEMBL28419452 0.68 CHRNA7 (0.39) CHRNA7ACHETDP1GAAMEN1
SCHEMBL28381315 0.67 CHRNA7 (0.43) CHRNA7ACHETDP1GAAMEN1
Hydrochloric Acid SCHEMBL1082197 0.67 CHRNA7 (0.38) CHRNA7ACHETDP1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed