SCHEMBL71109

SCHEMBL71109

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nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.57
FOLH1 Q04609 6/20 0.36
NOD1 Q9Y239 3/20 0.36
SELP P16109 1/20 0.36
CCKAR P32238 1/20 0.35
CCKBR P32239 1/20 0.35
GLO1 Q04760 1/20 0.34
RIMKLA Q8IXN7 1/20 0.34
NAALAD2 Q9Y3Q0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71091 1.00 GLP1R (0.57) GLP1RFOLH1NOD1SELPCCKAR
SCHEMBL72060 1.00 GLP1R (0.57) GLP1RFOLH1NOD1SELPCCKAR
SCHEMBL73258 0.92 GLP1R (0.55) GLP1RFOLH1CCKARCCKBR
SCHEMBL17551913 0.90 GLP1R (0.62) GLP1RFOLH1NOD1SELPCCKAR
SCHEMBL23874254 0.89 GLP1R (0.56) GLP1RFOLH1NOD1SELPCCKAR
SCHEMBL25662193 0.89 GLP1R (0.56) GLP1RFOLH1NOD1SELPCCKAR
SCHEMBL25662184 0.89 GLP1R (0.56) GLP1RFOLH1NOD1SELPCCKAR
SCHEMBL71989 0.89 GLP1R (0.52) GLP1RFOLH1NOD1SELPGLO1
SCHEMBL24284196 0.89 GLP1R (0.67) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL17570507 0.89 GLP1R (0.67) GLP1RFOLH1NOD1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129343-B2 Acylated GLP-1 compounds NOVO NORDISK A/S (DK) 2012-03-06 US disclosed
US-20090156478-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2009-06-18 US disclosed
US-20080207507-A1 Extended Glp-1 Compounds NOVO NORDISK A/S (DK) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207507-A1 Extended Glp-1 Compounds GLP1R, GIPR, IAPP GLP1R 1/4885FOLH1 274/4885NOD1 933/4885
US-20090156478-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR GLP1R 1/4885FOLH1 450/4885NOD1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.