Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 16/20 | 0.73 |
| ▸ | PDE1B | Q01064 | 16/20 | 0.73 |
| ▸ | PDE1C | Q14123 | 16/20 | 0.73 |
| ▸ | ESR1 | P03372 | 1/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.63 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.63 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148860 | 1.00 | PDE1A (0.73) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL407938 | 0.87 | PDE1A (0.72) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL285263 | 0.87 | PDE1A (0.72) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL285264 | 0.87 | PDE1A (0.72) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL18291033 | 0.86 | CYP19A1 (0.87) | PDE1APDE1BPDE1CESR1ESR2 | |
| Idoxifene SCHEMBL19217 | 0.85 | PDE1A (1.00) | PDE1APDE1BPDE1CESR1ESR2 | |
| Idoxifene SCHEMBL19216 | 0.85 | PDE1A (1.00) | PDE1APDE1BPDE1CESR1ESR2 | |
| Idoxifene SCHEMBL3774574 | 0.85 | PDE1A (1.00) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL10349389 | 0.84 | PDE1A (0.73) | PDE1APDE1BPDE1CESR1ESR2 | |
| SCHEMBL10608838 | 0.84 | PDE1A (0.73) | PDE1APDE1BPDE1CESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023264-B1 | NEW MARKER, PRODUCTION PROCESS AND USE THEREOF | QUIVY JACQUES (BE) | 2003-03-19 | — | — | EP | claimed |
| EP-1023264-B1 | NEW MARKER, PRODUCTION PROCESS AND USE THEREOF | QUIVY JACQUES (BE) | 2003-03-19 | — | — | EP | disclosed |