Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | GLP1R | P43220 | 2/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112592 | 1.00 | HDAC6 (0.63) | HDAC6GLP1RSLC15A1CCNT1CDK9 | |
| SCHEMBL7215024 | 0.89 | HDAC6 (0.74) | HDAC6GLP1RSLC15A1CCNT1CDK9 | |
| SCHEMBL10308324 | 0.89 | HDAC6 (0.74) | HDAC6GLP1RSLC15A1CCNT1CDK9 | |
| SCHEMBL7215020 | 0.89 | HDAC6 (0.74) | HDAC6GLP1RSLC15A1CCNT1CDK9 | |
| SCHEMBL7809958 | 0.88 | HDAC6 (0.83) | HDAC6GLP1RSLC15A1HSPA8 | |
| SCHEMBL7809963 | 0.88 | HDAC6 (0.83) | HDAC6GLP1RSLC15A1HSPA8 | |
| SCHEMBL7739904 | 0.81 | HDAC6 (0.63) | HDAC6SLC15A1CCNT1CDK9HSPA8 | |
| SCHEMBL7113212 | 0.80 | HDAC6 (0.62) | HDAC6GLP1RSLC15A1CCNT1CDK9 | |
| SCHEMBL7739171 | 0.80 | HDAC6 (0.53) | HDAC6SLC15A1CCNT1CDK9HSPA8 | |
| SCHEMBL7742235 | 0.80 | HDAC6 (0.64) | HDAC6GLP1RSLC15A1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | claimed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | claimed |
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |