Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863499 | 0.96 | MAP2K1 (0.53) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4856666 | 0.94 | MAP2K1 (0.50) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL7048023 | 0.93 | MAP2K1 (0.57) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL7047013 | 0.93 | MEN1 (0.47) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL7112331 | 0.92 | MAP2K1 (0.49) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4853410 | 0.89 | MAP2K1 (0.61) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4858224 | 0.89 | MEN1 (0.50) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4862287 | 0.88 | MAP2K1 (0.52) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4857212 | 0.88 | MAP2K1 (0.55) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL7052649 | 0.87 | MAP2K1 (0.49) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |