Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.75 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110078 | 0.95 | ESR1 (0.82) | ESR1ESR2F2 | |
| Hydrochloric Acid SCHEMBL7110093 | 0.94 | ESR1 (0.84) | ESR1ESR2F2 | |
| SCHEMBL7105804 | 0.89 | ESR1 (0.78) | ESR1ESR2F2 | |
| SCHEMBL6136016 | 0.89 | ESR1 (0.87) | ESR1ESR2F2 | |
| SCHEMBL3862974 | 0.89 | ESR1 (0.87) | ESR1ESR2F2 | |
| Hydrochloric Acid SCHEMBL1358943 | 0.88 | ESR1 (0.80) | ESR1ESR2F2 | |
| SCHEMBL7105849 | 0.88 | ESR1 (0.70) | ESR1ESR2F2 | |
| SCHEMBL6136011 | 0.88 | ESR1 (0.85) | ESR1ESR2F2 | |
| SCHEMBL13897795 | 0.88 | ESR1 (0.85) | ESR1ESR2F2 | |
| SCHEMBL7109026 | 0.88 | ESR1 (0.76) | ESR1ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100754-A1 | NAPHTHALENE COMPOUNDS, INTERMEDIATES, FORMULATIONS, AND METHODS | ELI LILLY AND COMPANY | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100754-A1 | NAPHTHALENE COMPOUNDS, INTERMEDIATES, FORMULATIONS, AND METHODS | NDC1, SQLE, NQO1 | ESR1 1044/4885ESR2 2130/4885HRH3 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.