Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087334 | 0.85 | SLC6A4 (1.00) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6087825 | 0.85 | SLC6A4 (0.82) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6087821 | 0.85 | SLC6A4 (0.82) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6088195 | 0.82 | SLC6A4 (1.00) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6087952 | 0.80 | SLC6A4 (1.00) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6111589 | 0.77 | SLC6A4 (0.75) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6086998 | 0.77 | SLC6A4 (1.00) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6087331 | 0.77 | SLC6A4 (1.00) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6087812 | 0.77 | SLC6A4 (0.73) | SLC6A4HTR1ADRD1SLC6A2HTR1B | |
| SCHEMBL6087829 | 0.77 | SLC6A4 (1.00) | SLC6A4HTR1ADRD1SLC6A2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026236-A2 | CYCLOPENTYL INDOLE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-01 | — | — | WO | claimed |