Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113403 | 0.95 | ADORA2A (0.61) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7114068 | 0.94 | ADORA2A (0.61) | ADORA2AADORA3ADORA2BADORA1 | |
| Formic Acid SCHEMBL7113401 | 0.91 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7113331 | 0.90 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL7114065 | 0.89 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7117090 | 0.87 | ADORA2A (0.52) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7114211 | 0.87 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7120929 | 0.85 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| Formic Acid SCHEMBL7114078 | 0.85 | ADORA2A (0.65) | ADORA2AADORA3ADORA2BADORA1 | |
| Formic Acid SCHEMBL7114062 | 0.85 | ADORA2A (0.65) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090020-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-05 | — | — | EP | disclosed |
| EP-1090020-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067263-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | disclosed |