⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920447 | 0.74 | — | — | |
| SCHEMBL11895879 | 0.74 | — | — | |
| SCHEMBL12477 | 0.74 | — | — | |
| SCHEMBL29331229 | 0.74 | — | — | |
| SCHEMBL21973805 | 0.74 | — | — | |
| SCHEMBL2302961 | 0.74 | — | — | |
| SCHEMBL18966048 | 0.74 | — | — | |
| SCHEMBL24372761 | 0.72 | — | — | |
| SCHEMBL12960883 | 0.72 | — | — | |
| SCHEMBL18884350 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10337039-B2 | Process for the preparation of chiral 2-aryl morpholines | HOFFMANN-LA ROCHE INC. (US) | 2019-07-02 | — | — | US | disclosed |
| EP-0901500-B1 | IN SITU PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN SYNTHESIS OF OLIGONUCLEOTIDES | AVECIA BIOTECHNOLOGY INC (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-0901500-A1 | $i(IN SITU) PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN SYNTHESIS OF OLIGONUCLEOTIDES | HYBRIDON, Inc. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042208-A1 | IN SITU PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN SYNTHESIS OF OLIGONUCLEOTIDES | HYBRIDON, INC. (US) | 1997-11-13 | — | — | WO | disclosed |