SCHEMBL711559

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL711181	0.95	GCK (0.45)	GCKCBFBPTGESALOX5PPARG
	SCHEMBL711044	0.92	GCK (0.46)	GCKCBFBKDM4EALDH1A1SMN1; SMN2
	SCHEMBL709496	0.89	PRMT5 (0.44)	GCKCBFBPTGESALOX5
	Trifluoroacetic Acid SCHEMBL720615	0.87	GCK (0.45)	GCKCBFBPTGESALOX5PPARG
	SCHEMBL2086932	0.87	GCK (0.43)	GCKCBFBHDAC3HDAC1HDAC2
	SCHEMBL712130	0.86	CBFB (0.41)	GCKCBFBACHEKDM4EALDH1A1
	SCHEMBL2668116	0.85	GCK (0.44)	GCKKDM4EALDH1A1SMN1; SMN2
	SCHEMBL10206659	0.83	DHODH (0.41)	GCKCBFBMMP13KDM4EALDH1A1
	SCHEMBL711346	0.83	GCK (0.47)	GCKCBFBPTGESALOX5ACHE
	SCHEMBL10206644	0.82	PRMT5 (0.46)	PTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.