Styrene

Styrene

SCHEMBL7116262

C=C(C)C(=O)OCCCCCCCCCCCC.C=CCOC(=O)C(=C)C.C=Cc1ccccc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
TDP1 Q9NUW8 2/20 0.46
POLB P06746 2/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 5/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 2/20 0.42
CYP3A4 P08684 2/20 0.42
TP53 P04637 1/20 0.42
KDM4E B2RXH2 4/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HSD17B10 Q99714 1/20 0.40
PPARG P37231 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1978653 0.94 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL6762849 0.94 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL4205045 0.94 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL1984291 0.94 TSHR (0.65) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL9305486 0.93 TSHR (0.63) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL26633376 0.93 TSHR (0.63) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL1930527 0.93 TSHR (0.62) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL8675033 0.91 TSHR (0.61) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL20543059 0.91 TSHR (0.61) TSHRTDP1POLBAPEX1HTT
Styrene SCHEMBL28611029 0.91 TSHR (0.61) TSHRTDP1POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1021472-B1 POLYMER COMPOSITION NAT STARCH CHEM INVEST (US) 2003-10-22 EP disclosed
US-6372846-B1 A POLY(ALKYL(METH)ACRYLATE) BASE POLYMER AND A RUBBER TOUGHENING AGENT PRESENT AS DISCRETE ISLANDS AND SUB-ISLANDS, CONFINED BY THE BASE POLYMER; MOULDINGS; IMPACT STRENGTH; EXTERNAL LIGHT CLUSTERS FOR AUTOMOBILES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2002-04-16 US disclosed