Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734915 | 1.00 | TAAR1 (0.70) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL8571535 | 1.00 | TAAR1 (0.70) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL20146704 | 0.97 | TAAR1 (0.73) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL20135772 | 0.92 | TAAR1 (0.73) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL16289455 | 0.89 | TAAR1 (0.57) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL4445549 | 0.89 | TAAR1 (0.57) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL271466 | 0.89 | TAAR1 (0.57) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL271561 | 0.89 | TAAR1 (0.57) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL8099646 | 0.89 | TAAR1 (0.76) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL272341 | 0.89 | TAAR1 (0.57) | TAAR1TSHRADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824706-B2 | OXIDATIVE STABILITY; PROCESSIBILITY; EASY TO SYNTHESIZE; HIGH CHARGE MOBILITY | MERCK PATENT GESELLSCHAFT MIT BESCHRANK HAFTUNG (DE) | 2004-11-30 | — | — | US | disclosed |
| US-20030062536-A1 | Mono-, oligo- and poly-difluorovinyl-(hetero)arylenes, their synthesis and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2003-04-03 | — | — | US | disclosed |
| EP-1279691-A1 | Mono-, oligo- and poly-difluorovinyl-(hetero)arylenes, their synthesis and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-01-29 | — | — | EP | disclosed |