Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27033104 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL1006745 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL27033077 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL3437057 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL8091612 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL1449856 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL2854923 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL5573865 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Bromide SCHEMBL20541362 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29484169 | 0.98 | TSHR (0.71) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667476-A1 | NOVEL MITOCHONDRIA-TARGETING COMPOUNDS | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2025-12-24 | — | — | EP | claimed |
| CN-119661745-A | Film-coating fresh-keeping material, and preparation method and application thereof | 中国热带农业科学院农产品加工研究所 | 2025-03-21 | — | — | CN | claimed |
| CN-119592142-A | Natural antibacterial film-coating fresh-keeping material and preparation method and application thereof | 中国热带农业科学院南亚热带作物研究所 | 2025-03-11 | — | — | CN | claimed |
| CN-118772304-A | Quaternary phosphonium pullulan and preparation method and application thereof | 烟台先进材料与绿色制造山东省实验室 | 2024-10-15 | — | — | CN | claimed |
| WO-2024172390-A1 | NOVEL MITOCHONDRIA-TARGETING COMPOUNDS | 가톨릭대학교 산학협력단 | 2024-08-22 | — | — | WO | claimed |
| CN-118178670-A | Preparation method of novel targeted mitochondrial antioxidant and application of novel targeted mitochondrial antioxidant in resisting autoimmune hepatitis | 华中科技大学 | 2024-06-14 | — | — | CN | claimed |
| WO-2023137518-A1 | PLATINUM COMPLEXES | Western Sydney University (AU) | 2023-07-27 | — | — | WO | claimed |
| CN-115337297-A | CPI-613 mitochondrion targeted small molecule prodrug, self-assembled nanoparticles thereof, preparation method and application | 沈阳药科大学 | 2022-11-15 | — | — | CN | claimed |
| CN-113476426-A | Preparation of double-targeting functional factor delivery system based on hyaluronic acid and application of double-targeting functional factor delivery system in inflammatory bowel disease | 大连工业大学 | 2021-10-08 | — | — | CN | claimed |
| CN-113278093-A | Chitosan quaternary ammonium salt quaternary phosphonium salt derivative and preparation method and application thereof | 中国热带农业科学院南亚热带作物研究所 | 2021-08-20 | — | — | CN | claimed |
| CN-113183275-A | High-density fiberboard with antibacterial function and manufacturing process thereof | 佳诺威集团股份有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-112662026-A | Manufacturing process of medical disposable glove material | 李林 | 2021-04-16 | — | — | CN | claimed |
| EP-4739696-A1 | MITOCHONDRIA SPECIFIC TRANSCRIPTION INHIBITOR COMPOUNDS | Lunella Biotech, Inc. (CA) | 2026-05-13 | — | — | EP | disclosed |
| EP-4667476-A1 | NOVEL MITOCHONDRIA-TARGETING COMPOUNDS | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2025-12-24 | — | — | EP | disclosed |
| EP-4661876-A1 | METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF | University of Miami (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250161476-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3987072-A | CIS-4,5-Didehydro-15- or 16-alkylated 11-deoxy-PGE1 analogs | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3962293-A | 13,14-Dihydro-16-fluoro prostaglandin F1 | THE UPJOHN COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3947469-A | PROSTAGLANDIN INTERMEDIATES | RECHERCHE ET INDUSTRIE THERAPEUTIQUES (R.I.T.) (BE) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161476-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF | GLP1R, GIPR, GCGR | TSHR 151/4885ALDH1A1 2596/4885CYP1A2 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.