Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117394 | 0.86 | CHRM2 (0.48) | CHRM2CHRM4CHRM1CHRM3ABCB1 | |
| SCHEMBL7122471 | 0.85 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3ABCB1 | |
| SCHEMBL7118400 | 0.82 | CHRM2 (0.45) | CHRM2CHRM4CHRM1CHRM3ABCB1 | |
| SCHEMBL5096532 | 0.81 | KDM4E (0.48) | ALDH1A1MEN1KMT2ASTSNPC1 | |
| SCHEMBL7119173 | 0.81 | MEN1 (0.54) | CHRM2CHRM4CHRM1CHRM3ABCB1 | |
| SCHEMBL26923461 | 0.81 | MAPT (0.47) | CHRM2CHRM4CHRM1CHRM3ABCB1 | |
| SCHEMBL5406440 | 0.80 | DPP4 (0.52) | CHRM2CHRM4CHRM1CHRM3POLB | |
| SCHEMBL30702506 | 0.80 | CYP3A4 (0.48) | CHRM2CHRM4CHRM1CHRM3ABCB1 | |
| SCHEMBL13509200 | 0.79 | POLB (0.46) | CHRM2CHRM4CHRM1CHRM3POLB | |
| SCHEMBL26922383 | 0.78 | NPC1 (0.45) | CHRM2CHRM4CHRM1CHRM3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |