⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801590 | 0.80 | — | — | |
| SCHEMBL7981771 | 0.76 | — | — | |
| SCHEMBL15683190 | 0.76 | — | — | |
| SCHEMBL6647445 | 0.76 | — | — | |
| SCHEMBL2006355 | 0.76 | — | — | |
| SCHEMBL20877696 | 0.76 | HRH4 (0.55) | — | |
| SCHEMBL25374785 | 0.76 | — | — | |
| SCHEMBL20307127 | 0.76 | — | — | |
| SCHEMBL3926222 | 0.76 | — | — | |
| SCHEMBL10858595 | 0.74 | HRH3 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289833-A1 | TYK2 INHIBITOR COMPOUND CONTAINING BICYCLIC RING | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-12-13 | — | — | EP | disclosed |
| US-20210188814-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED (GB) | 2021-06-24 | — | — | US | disclosed |
| WO-2021113669-A1 | CANNABINOIDS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021113656-A1 | CANNABINOIDS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
| US-10428095-B2 | Compounds for treatment of complement mediated disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190031692-A1 | COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2019-01-31 | — | — | US | disclosed |
| EP-3380469-A1 | BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2018-10-03 | — | — | EP | disclosed |
| WO-2017091661-A1 | BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF | STROVEL JEFFREY WILLIAM (US) | 2017-06-01 | — | — | WO | disclosed |
| WO-2016096589-A1 | SYNTHETIC ENZYME MIMIC BASED ON A HISTIDINE SCAFFOLD | UNILEVER PLC (GB) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016096590-A1 | SYNTHETIC ENZYME MIMIC BASED ON A HISTIDINE SCAFFOLD | UNILEVER PLC (GB) | 2016-06-23 | — | — | WO | disclosed |
| WO-2003028739-A2 | COMPOSITION FOR PREVENTING OR TREATING HYPERLIPIDEMIA OR HYPERGLYCEMIA COMPRISING A POLYMER OR ITS SALT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |