Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | CCR4 | P51679 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117156 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL7116863 | 0.87 | KDM4E (0.66) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL7116850 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL5436842 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL5088527 | 0.80 | ESR1 (0.88) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL15842938 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HPGDGAAMAOB | |
| SCHEMBL26743702 | 0.79 | HPGD (0.78) | KDM4EALDH1A1HPGDGAAMAOB | |
| SCHEMBL7113499 | 0.78 | ESR2 (0.60) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL7115086 | 0.78 | ESR1 (0.51) | KDM4EALDH1A1HPGDGAAESR2 | |
| SCHEMBL7120274 | 0.78 | ESR2 (0.59) | ESR2ESR1MAOBMAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |