Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.63 |
| ▸ | NPY1R | P25929 | 10/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.63 |
| ▸ | NPY2R | P49146 | 6/20 | 0.63 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.53 |
| ▸ | CHRNG | P07510 | 1/20 | 0.53 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.53 |
| ▸ | CHRND | Q07001 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143658 | 1.00 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL7119652 | 1.00 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL30608889 | 1.00 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL29625340 | 1.00 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL29641074 | 1.00 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL30565146 | 0.97 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL30036967 | 0.96 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL29483767 | 0.96 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2RCHRNA1 | |
| SCHEMBL30118077 | 0.95 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2RERAP2 | |
| SCHEMBL29637467 | 0.95 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358342-A2 | RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM | The Children's Medical Center Corporation (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059338-A2 | RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |
| US-6303116-B1 | CAPABLE OF TRANSDUCING THERAPEUTIC GENES INTO NON-DIVIDING CELLS. | THOMAS JEFFERSON UNIVERSITY | 2001-10-16 | — | — | US | disclosed |