Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119720 | 1.00 | HTR2C (0.68) | HTR2CDRD2ADRA1AHTR2AHTR2B | |
| SCHEMBL7119711 | 1.00 | HTR2C (0.68) | HTR2CDRD2ADRA1AHTR2AHTR2B | |
| SCHEMBL7353514 | 0.86 | HTR2C (0.56) | HTR2CDRD2ADRA1AHTR2AHTR2B | |
| SCHEMBL7380631 | 0.86 | HTR2C (0.56) | HTR2CDRD2ADRA1AHTR2AHTR2B | |
| SCHEMBL7380627 | 0.86 | HTR2C (0.56) | HTR2CDRD2ADRA1AHTR2AHTR2B | |
| SCHEMBL18618488 | 0.84 | HTR2C (0.48) | HTR2CDRD2ADRA1AHTR2A | |
| SCHEMBL5758612 | 0.84 | SLC6A2 (0.47) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5758608 | 0.84 | SLC6A2 (0.47) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5757803 | 0.84 | SLC6A2 (0.47) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7970364 | 0.84 | SLC6A2 (0.47) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092733-A1 | Process for preparing trans-2,4-disubstituted piperidines | ELI LILLY AND COMPANY | 2003-05-15 | — | — | US | disclosed |
| EP-1244622-A1 | A PROCESS FOR PREPARING TRANS-2,4-DISUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001046143-A1 | A PROCESS FOR PREPARING TRANS-2,4-DISUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092733-A1 | Process for preparing trans-2,4-disubstituted piperidines | CYP4B1, CYP1A1, CYP3A4 | HTR2C 178/4885DRD2 266/4885ADRA1A 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.