Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.35 |
| ▸ | EPM2A | O95278 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPRG | P23470 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PTPN3 | P26045 | 1/20 | 0.35 |
| ▸ | PTPRM | P28827 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.35 |
| ▸ | PTPN14 | Q15678 | 1/20 | 0.35 |
| ▸ | PTPN21 | Q16825 | 1/20 | 0.35 |
| ▸ | UBLCP1 | Q8WVY7 | 1/20 | 0.35 |
| ▸ | DUSP23 | Q9BVJ7 | 1/20 | 0.35 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121297 | 1.00 | FYN (0.40) | FYNDYRK1AKDRPTPN11EPM2A | |
| SCHEMBL7124267 | 0.88 | DYRK1A (0.46) | FYNDYRK1AKDRIDO1GSK3B | |
| SCHEMBL7122931 | 0.86 | FYN (0.42) | FYNDYRK1AKDRFGFR3IDO1 | |
| SCHEMBL7122934 | 0.86 | FYN (0.42) | FYNDYRK1AKDRFGFR3IDO1 | |
| SCHEMBL7121299 | 0.82 | DYRK1A (0.35) | FYNDYRK1AIDO1GSK3BMC4R | |
| SCHEMBL7117407 | 0.82 | DYRK1A (0.41) | FYNDYRK1AKDRFGFR3GSK3B | |
| SCHEMBL7117409 | 0.82 | DYRK1A (0.41) | FYNDYRK1AKDRFGFR3GSK3B | |
| SCHEMBL7128685 | 0.74 | DYRK1A (0.40) | FYNDYRK1AKDRFGFR3GSK3B | |
| SCHEMBL7128690 | 0.74 | DYRK1A (0.40) | FYNDYRK1AKDRFGFR3GSK3B | |
| SCHEMBL7120246 | 0.73 | FYN (0.47) | FYNDYRK1AKDRIDO1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | FYN 817/4885DYRK1A 3357/4885KDR 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.