Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 9/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.64 |
| ▸ | CDK2 | P24941 | 6/20 | 0.64 |
| ▸ | CDK1 | P06493 | 2/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.64 |
| ▸ | GRM5 | P41594 | 6/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | CCND3 | P30281 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127547 | 0.80 | CCNA2 (0.40) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL7125143 | 0.80 | IKBKB (0.49) | CCNA2CDK2CDK1CCNB1CCNT1 | |
| SCHEMBL7128029 | 0.75 | IGF1R (0.48) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL9960032 | 0.74 | GRM5 (1.00) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL9959836 | 0.73 | CDK5 (1.00) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL7128258 | 0.69 | NPC1 (0.39) | CDK2CDK1CCNB1CCNT1CCNE1 | |
| SCHEMBL7120305 | 0.67 | KDR (0.60) | — | |
| SCHEMBL7126117 | 0.66 | RIPK2 (0.41) | WNT1GSK3BDYRK1A | |
| SCHEMBL7121414 | 0.66 | TP53 (0.57) | TP53MAPT | |
| SCHEMBL7121296 | 0.66 | CYP1A2 (0.50) | WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | CDK5 2255/4885CDK5R1 2841/4885CCNA2 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.