Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 7/20 | 0.48 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.48 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119560 | 0.74 | IP6K1 (0.41) | IP6K1IP6K3IP6K2HTTDAPK3 | |
| SCHEMBL7127240 | 0.73 | HPGD (0.40) | HTTDAPK3PRKD3PIM1GSK3A | |
| SCHEMBL7118477 | 0.72 | IP6K1 (0.39) | IP6K1IP6K3IP6K2HTTDAPK3 | |
| SCHEMBL7129547 | 0.72 | PDPK1 (0.38) | IP6K1IP6K3IP6K2HTTDAPK3 | |
| SCHEMBL7118113 | 0.72 | JAK2 (0.38) | IP6K1IP6K3IP6K2HTTDAPK3 | |
| SCHEMBL7119830 | 0.71 | PDPK1 (0.40) | HTTDAPK3PRKD3PIM1GSK3A | |
| SCHEMBL7127142 | 0.70 | PDPK1 (0.41) | HTTDAPK3PRKD3PIM1GSK3A | |
| SCHEMBL7125512 | 0.69 | PIM1 (0.42) | HTTDAPK3PRKD3PIM1GSK3A | |
| SCHEMBL7127071 | 0.68 | PDPK1 (0.37) | HTTDAPK3PRKD3PIM1GSK3A | |
| SCHEMBL7124624 | 0.68 | PDPK1 (0.39) | HTTDAPK3PRKD3PIM1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | IP6K1 804/4885IP6K3 434/4885IP6K2 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.