Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709413 | 0.82 | PTGDR2 (0.38) | MEN1KMT2AGAARAB9APTGDR2 | |
| SCHEMBL710466 | 0.80 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL711075 | 0.71 | PTGDR2 (0.43) | PTGDR2MAPK1 | |
| SCHEMBL708188 | 0.67 | PTGDR2 (0.53) | PTGDR2MAPK1 | |
| SCHEMBL710595 | 0.67 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL1566971 | 0.66 | HDAC3 (0.46) | MEN1KMT2AGAALMNAHTT | |
| SCHEMBL1566235 | 0.66 | HDAC3 (0.46) | MEN1KMT2AGAALMNAHTT | |
| SCHEMBL710381 | 0.65 | PTGDR2 (0.44) | MEN1KMT2AGAARAB9APTGDR2 | |
| SCHEMBL710096 | 0.64 | PTGDR2 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL708384 | 0.64 | PTGDR2 (0.40) | MEN1KMT2AGAARAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124629-B2 | Naphthylacetic acids | HOFFMANN-LA ROCHE INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2346807-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | disclosed |