SCHEMBL7121990

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7117333	0.83	ABL1 (0.54)	EGFRABL1PDGFRBBCRSRC
	SCHEMBL21362368	0.77	CYP3A4 (0.62)	ABL1PDGFRBBCRSRCPDGFRA
	SCHEMBL7123001	0.76	ABL1 (0.42)	KDRABL1PDGFRBBCRSRC
	SCHEMBL7130668	0.76	ABL1 (0.53)	ABL1PDGFRBBCRSRCPDGFRA
	SCHEMBL7123054	0.76	KDR (0.59)	EGFRKDRPDGFRBPDGFRA
	SCHEMBL479267	0.73	EGFR (0.76)	EGFRKDRCYP3A4KDM4ETP53
	SCHEMBL31426459	0.73	EGFR (0.76)	EGFRKDRCYP3A4KDM4ETP53
	SCHEMBL4820797	0.73	SMN1; SMN2 (0.59)	EGFRKDRPDGFRBCYP3A4KDM4E
	SCHEMBL4783313	0.73	EGFR (0.58)	EGFRKDRSYKCYP3A4KDM4E
	SCHEMBL8592858	0.73	ABL1 (0.67)	EGFRABL1PDGFRBBCRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.