Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720357 | 0.84 | GAA (0.49) | AREGLN1CACNA1HKDM4EALDH1A1 | |
| SCHEMBL439758 | 0.84 | GAA (0.49) | AREGLN1CACNA1HKDM4EALDH1A1 | |
| SCHEMBL7734462 | 0.78 | AR (0.40) | AREGLN1KDM4EALDH1A1 | |
| SCHEMBL13542746 | 0.78 | KDM4E (0.50) | AREGLN1CACNA1HKDM4EALDH1A1 | |
| SCHEMBL7113015 | 0.77 | EGLN1 (0.39) | AREGLN1KDM4EALDH1A1 | |
| SCHEMBL13408169 | 0.76 | MAPT (0.57) | AREGLN1CACNA1HKDM4EALDH1A1 | |
| SCHEMBL2418522 | 0.76 | EGLN1 (0.49) | AREGLN1CACNA1HKDM4EHCRTR1 | |
| SCHEMBL7214338 | 0.74 | KDM4E (0.43) | EGLN1KDM4EALDH1A1 | |
| SCHEMBL18659702 | 0.74 | AR (0.50) | AREGLN1CACNA1HKDM4EALDH1A1 | |
| SCHEMBL14531739 | 0.73 | EGLN1 (0.47) | AREGLN1CACNA1HKDM4EHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |