Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45305 | 0.91 | TSHR (0.47) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL5243510 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL14312417 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL245113 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL3545311 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL4150786 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL2864476 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL3545968 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL4163075 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 | |
| SCHEMBL17807067 | 0.89 | MEN1 (0.58) | TSHRCTHCBSTHPOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223951-A4 | METHOD OF PREVENTING ADHESIONS WITH ABSORBABLE POLYOXAESTERS | ETHICON INC (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1223951-A1 | METHOD OF PREVENTING ADHESIONS WITH ABSORBABLE POLYOXAESTERS | ETHICON, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001012203-A1 | METHOD OF PREVENTING ADHESIONS WITH ABSORBABLE POLYOXAESTERS | ETHICON, INC. (US) | 2001-02-22 | — | — | WO | disclosed |