Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.85 |
| ▸ | CA1 | P00915 | 1/20 | 0.85 |
| ▸ | CA2 | P00918 | 1/20 | 0.85 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | XDH | P47989 | 1/20 | 0.62 |
| ▸ | GAPDH | P04406 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124497 | 0.91 | MAOB (0.86) | MAOBCA1CA2ACHEXDH | |
| SCHEMBL7120318 | 0.89 | NPC1 (0.75) | MAOBCA1CA2ACHEKMT2A | |
| SCHEMBL7117976 | 0.86 | MAOB (0.78) | MAOBCA1CA2ACHEXDH | |
| SCHEMBL22132856 | 0.86 | MAOB (0.78) | MAOBCA1CA2ACHEXDH | |
| SCHEMBL7123257 | 0.86 | NPC1 (0.79) | MAOBCA1CA2ACHEGAPDH | |
| SCHEMBL29427489 | 0.84 | MAPT (0.67) | MAOBCA1CA2KDM4EKMT2A | |
| SCHEMBL5940938 | 0.84 | MAPT (0.67) | MAOBCA1CA2KDM4EKMT2A | |
| SCHEMBL22132869 | 0.83 | MAOB (1.00) | MAOBCA1CA2ACHEXDH | |
| SCHEMBL22132870 | 0.82 | MAOB (0.82) | MAOBCA1CA2ACHEGAPDH | |
| SCHEMBL17857190 | 0.82 | MAOB (1.00) | MAOBCA1CA2XDHTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |