SCHEMBL71225

SCHEMBL71225

CCOCCOCCNC(=O)CCOCCOCCNC(=O)COCCOCCNC(=O)CCC(NC(=O)CC)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.56
SELP P16109 1/20 0.41
NOD1 Q9Y239 5/20 0.38
FOLH1 Q04609 3/20 0.37
CCKAR P32238 2/20 0.36
CCKBR P32239 2/20 0.36
C3AR1 Q16581 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71066 0.98 GLP1R (0.58) GLP1RSELPNOD1CCKARCCKBR
SCHEMBL15871523 0.92 GLP1R (0.55) GLP1RSELPNOD1
SCHEMBL71221 0.91 GLP1R (0.61) GLP1RSELPNOD1CCKARCCKBR
SCHEMBL19261638 0.91 GLP1R (0.61) GLP1RSELPNOD1CCKARCCKBR
SCHEMBL13184775 0.89 GLP1R (0.57) GLP1RSELPNOD1FOLH1CCKAR
SCHEMBL15002746 0.88 GLP1R (0.56) GLP1RSELPNOD1FOLH1
SCHEMBL15002721 0.87 GLP1R (0.57) GLP1RSELPNOD1CCKARCCKBR
SCHEMBL14478727 0.87 GLP1R (0.56) GLP1RSELPNOD1FOLH1
SCHEMBL17131127 0.87 GLP1R (0.54) GLP1RSELPNOD1FOLH1CCKAR
SCHEMBL15871484 0.86 GLP1R (0.65) GLP1RSELPNOD1FOLH1CCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129343-B2 Acylated GLP-1 compounds NOVO NORDISK A/S (DK) 2012-03-06 US disclosed
US-20090156478-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2009-06-18 US disclosed
US-20080207507-A1 Extended Glp-1 Compounds NOVO NORDISK A/S (DK) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207507-A1 Extended Glp-1 Compounds GLP1R, GIPR, IAPP GLP1R 1/4885SELP 1046/4885NOD1 933/4885
US-20090156478-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR GLP1R 1/4885SELP 1274/4885NOD1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.