SCHEMBL7122854

SCHEMBL7122854

NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CN)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC15A2 Q16348 1/20 0.59
CHRND Q07001 6/20 0.54
CHRNA1 P02708 2/20 0.54
CHRNG P07510 2/20 0.54
CHRNB1 P11230 2/20 0.54
ERAP2 Q6P179 1/20 0.54
LNPEP Q9UIQ6 1/20 0.54
NPY1R P25929 1/20 0.51
NPY2R P49146 1/20 0.51
NPY4R P50391 1/20 0.51
GRIA1 P42261 4/20 0.50
ENPEP Q07075 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7122844 1.00 SLC15A2 (0.59) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL9318080 0.99 SLC15A2 (0.60) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL9318061 0.99 SLC15A2 (0.60) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL29980121 0.96 SLC15A2 (0.54) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL29630584 0.91 CHRND (0.53) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL29476550 0.91 CHRNA1 (0.56) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL1711945 0.89 SLC15A2 (0.62) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL1711937 0.89 SLC15A2 (0.62) SLC15A2CHRNDCHRNA1CHRNGCHRNB1
SCHEMBL24122752 0.89 CHRND (0.56) CHRNDCHRNA1CHRNGCHRNB1GRIA1
SCHEMBL7866097 0.89 CHRND (0.56) CHRNDCHRNA1CHRNGCHRNB1GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1358342-A2 RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM The Children's Medical Center Corporation (US) 2003-11-05 EP disclosed
WO-2002059338-A2 RETROVIRAL VECTORS FOR TRANSDUCTION INTO QUIESCENT CELLS AND PACKAGING SYSTEMS FOR THEM THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2002-08-01 WO disclosed
US-6303116-B1 CAPABLE OF TRANSDUCING THERAPEUTIC GENES INTO NON-DIVIDING CELLS. THOMAS JEFFERSON UNIVERSITY 2001-10-16 US disclosed