SCHEMBL7123460

SCHEMBL7123460

CC(C)OP(=O)(S)SC(C)C.[Ni]

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.39
ACHE P22303 1/20 0.39
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1531694 0.98 CTSA (0.40) CTSAACHEALDH1A1L3MBTL1
SCHEMBL345421 0.95 CTSA (0.39) CTSAACHEALDH1A1L3MBTL1
SCHEMBL3680796 0.95 CTSA (0.39) CTSAACHEALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL10893617 0.95 CTSA (0.39) CTSAACHEALDH1A1L3MBTL1
SCHEMBL11700965 0.95 CTSA (0.39) CTSAACHEALDH1A1L3MBTL1
SCHEMBL11705248 0.95 CTSA (0.39) CTSAACHEALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL18047232 0.93 CTSA (0.37) CTSAACHE
Putrescine SCHEMBL8199420 0.84 CTSA (0.31) CTSAACHE
SCHEMBL4652435 0.74 CTSA (0.33) CTSAACHE
SCHEMBL1606168 0.72 CTSA (0.43) CTSAACHEALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195898-B1 A METHOD OF INCREASING THE LIGHT FATIGUE RESISTANCE OF A PHOTOCHROMIC COMPOSITION AND PHOTOCHROMIC COMPOSITION AMERICAN OPTICAL CORPORATION (US) 1988-11-02 EP claimed
US-4720356-A Photochromic composition resistant to fatigue AMERICAN OPTICAL CORPORATION (US) 1988-01-19 US claimed
EP-0195898-A1 A method of increasing the light fatigue resistance of a photochromic composition and photochromic composition AMERICAN OPTICAL CORPORATION (US) 1986-10-01 EP claimed
EP-0628064-B2 PHOTOCHROMIC NAPHTHOPYRANS TRANSITIONS OPTICAL INC (US) 2003-12-10 EP disclosed
EP-0628064-B1 PHOTOCHROMIC NAPHTHOPYRANS TRANSITIONS OPTICAL INC (US) 1999-04-07 EP disclosed
EP-0560898-B1 PHOTOCHROMIC NAPHTHOPYRANS PPG INDUSTRIES INC (US) 1997-03-26 EP disclosed
US-5585042-A REVERSIBLE CHANGE IN COLOR WHEN EXPOSURED TO ULTRAVIOLET RADIATION TRANSITIONS OPTICAL, INC. (US) 1996-12-17 US disclosed
EP-0540690-B1 PHOTOCHROMIC CHROMENE COMPOUNDS PPG INDUSTRIES INC (US) 1996-05-29 EP disclosed
EP-0628064-A4 PHOTOCHROMIC NAPHTHOPYRANS. PPG INDUSTRIES INC (US) 1995-02-08 EP disclosed
EP-0628064-A1 PHOTOCHROMIC NAPHTHOPYRANS TRANSITIONS OPTICAL, INC. (US) 1994-12-14 EP disclosed
US-5369158-A And polymer TRANSITIONS OPTICAL, INC. (US) 1994-11-29 US disclosed
WO-1993017071-A1 PHOTOCHROMIC NAPHTHOPYRANS PPG INDUSTRIES, INC. (US) 1993-09-02 WO disclosed
US-5238981-A PHOTOCHROMIC NAPHTHOPYRANS TRANSITIONS OPTICAL, INC. (US) 1993-08-24 US disclosed
EP-0540690-A1 PHOTOCHROMIC CHROMENE COMPOUNDS. PPG INDUSTRIES INC (US) 1993-05-12 EP disclosed
US-5200116-A Which experience a reversible change from colorless to orange upon exposure to sunlight PPG INDUSTRIES, INC. (US) 1993-04-06 US disclosed
EP-0540690-A4 PHOTOCHROMIC CHROMENE COMPOUNDS. PPG INDUSTRIES INC (US) 1993-02-12 EP disclosed
EP-0195898-B1 A METHOD OF INCREASING THE LIGHT FATIGUE RESISTANCE OF A PHOTOCHROMIC COMPOSITION AND PHOTOCHROMIC COMPOSITION AMERICAN OPTICAL CORPORATION (US) 1988-11-02 EP disclosed
US-4720356-A Photochromic composition resistant to fatigue AMERICAN OPTICAL CORPORATION (US) 1988-01-19 US disclosed
EP-0195898-A1 A method of increasing the light fatigue resistance of a photochromic composition and photochromic composition AMERICAN OPTICAL CORPORATION (US) 1986-10-01 EP disclosed
US-4018604-A METAL DITHIOCARBAMATES-DITHIOPHOSPHINATES TO PREVENT FOGGING HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1977-04-19 US disclosed