SCHEMBL7123768

SCHEMBL7123768

CC(C)c1ccc2c(c1-c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C=C(c1ccccc1)C2C[SiH2]CC1C(c2ccccc2)=Cc2c1ccc(C(C)C)c2-c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608755 0.85 TACR1 (0.34) CNR1CNR2
SCHEMBL7129709 0.82
SCHEMBL5609967 0.81 PDE2A (0.30)
SCHEMBL5721179 0.80 PTPN5 (0.32) PTPN5CNR1CNR2
SCHEMBL5610492 0.79 TACR1 (0.33) CNR1CNR2RAF1
SCHEMBL5609121 0.77 PTPN5 (0.30) PTPN5
SCHEMBL5610424 0.76 TACR1 (0.34)
SCHEMBL5721454 0.75
SCHEMBL5721228 0.75
SCHEMBL5609922 0.75 AKR1C3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456217-A1 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2004-09-15 EP disclosed
WO-2003050131-A1 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-06-19 WO disclosed