Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107457 | 0.81 | TLR7 (0.50) | TLR8TLR7TP53MAPT | |
| SCHEMBL6106550 | 0.81 | TLR8 (0.62) | TLR8TLR7TP53MAPTSMN1; SMN2 | |
| SCHEMBL6103486 | 0.80 | TLR8 (0.49) | TLR8TLR7TP53MAPTSMN1; SMN2 | |
| SCHEMBL6107164 | 0.78 | TLR7 (0.66) | TLR8TLR7NUDT1 | |
| SCHEMBL6106004 | 0.78 | TLR7 (0.60) | TLR8TLR7 | |
| SCHEMBL6105409 | 0.77 | HRH1 (0.50) | TLR8TLR7 | |
| SCHEMBL6106367 | 0.77 | TLR7 (0.63) | TLR8TLR7 | |
| SCHEMBL6105631 | 0.77 | TLR7 (0.73) | TLR8TLR7 | |
| SCHEMBL6104415 | 0.75 | TLR8 (0.63) | TLR8TLR7TP53MAPTNUDT1 | |
| SCHEMBL6105703 | 0.75 | TLR7 (0.52) | TLR8TLR7TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670372-B2 | Immunomodulators, for inducing cytokine biosynthesis in animals, and in the treatment of viral and neoplastic diseases; imidazo(4,5-c) quinoline-4-amine compounds that have an ether containing substituent at the 1-position | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-30 | — | — | US | disclosed |