Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 15/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCND2 | P30279 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750445 | 0.89 | HCRTR1 (0.37) | CETPHCRTR1HCRTR2AKT1CCNB2 | |
| SCHEMBL7123401 | 0.84 | HCRTR1 (0.38) | CETPHCRTR1HCRTR2CCNB2CCNE2 | |
| SCHEMBL7117716 | 0.84 | CETP (0.37) | CETPHCRTR1HCRTR2CCNB2CCNE2 | |
| SCHEMBL5754477 | 0.84 | CETP (0.37) | CETPHCRTR1HCRTR2 | |
| SCHEMBL5752033 | 0.83 | CETP (0.39) | CETPHCRTR1HCRTR2 | |
| SCHEMBL5753523 | 0.80 | HCRTR1 (0.37) | CETPHCRTR1HCRTR2 | |
| SCHEMBL5750077 | 0.80 | CETP (0.38) | CETPHCRTR1HCRTR2CCNB2CCNE2 | |
| SCHEMBL5749800 | 0.79 | HCRTR1 (0.40) | CETPHCRTR1HCRTR2 | |
| SCHEMBL5753117 | 0.78 | CETP (0.46) | CETP | |
| SCHEMBL5753905 | 0.77 | CETP (0.38) | CETPHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |