⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244854 | 0.79 | — | — | |
| SCHEMBL6238715 | 0.76 | — | — | |
| SCHEMBL6244125 | 0.74 | LCK (0.56) | — | |
| SCHEMBL8372038 | 0.74 | — | — | |
| SCHEMBL6241700 | 0.74 | LCK (0.56) | — | |
| SCHEMBL6240694 | 0.74 | LCK (0.56) | — | |
| SCHEMBL6241560 | 0.74 | LCK (0.56) | — | |
| SCHEMBL6240631 | 0.74 | LCK (0.56) | — | |
| SCHEMBL6241408 | 0.74 | — | — | |
| SCHEMBL1001541 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938426-A | Method for preparing AgI quantum dots through supermolecular polymer network limitation | 西北师范大学 | 2020-03-31 | — | — | CN | claimed |
| CN-115672295-B | Preparation and application of imine type column [5] arene modified silica gel chromatographic packing | 中国科学院兰州化学物理研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-112778156-B | Bishydrazide structure compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-14 | — | — | CN | disclosed |
| EP-3660023-B1 | THIENOPYRIMIDINEDIONE COMPOUNDS AS ACC INHIBITORS AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2023-03-08 | — | — | EP | disclosed |
| CN-115672295-A | Preparation and application of imine column [5] arene modified silica gel chromatographic packing | 中国科学院兰州化学物理研究所 | 2023-02-03 | — | — | CN | disclosed |
| EP-3752492-B1 | FUNGICIDAL OXADIAZOLES | BAYER AG (DE) | 2022-12-21 | — | — | EP | disclosed |
| CN-115215847-A | KRAS-SOS1 inhibitor, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-10-21 | — | — | CN | disclosed |
| CN-109305976-B | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110959007-B | Compounds as ACC inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-3986877-A1 | HYDROXYISOXAZOLINES AND DERIVATIVES THEREOF | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |
| US-5273998-A | Process for making an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5177216-A | DIASTEREOMERIC ESTER COMPOUND USEFUL AS AN INTERMEDIATE IN THE MAKING OF AN OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0456266-A1 | Method for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds, intermediates therefor and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-11-13 | — | — | EP | disclosed |
| US-5006534-A | Substituted ethers, thioethers and amines for use as lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| US-4952598-A | CALCIUM ANTAGONISTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
| US-4882329-A | CALCIUM CHANNEL BLOCKERS; CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4771062-A | ENZYME INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |