Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 11/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.82 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | GLA | P06280 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023180 | 1.00 | MIF (1.00) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL2166723 | 0.91 | ESR2 (1.00) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL1325165 | 0.85 | MIF (1.00) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL8934492 | 0.85 | ESR2 (0.82) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL14549127 | 0.85 | ESR2 (0.82) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL591688 | 0.84 | MIF (1.00) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL8117543 | 0.84 | MIF (1.00) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL8118640 | 0.83 | PON1 (0.73) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL28142014 | 0.83 | PTGS1 (1.00) | MIFESR2RAB9AMEN1KMT2A | |
| SCHEMBL7123294 | 0.82 | MIF (0.72) | MIFESR2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-2020130120-A1 | CANCER METASTASIS INHIBITOR | 学校法人京都薬科大学 | 2020-06-25 | — | — | WO | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |