Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153185 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2GAAMAPTMAPK1TDP1 | |
| SCHEMBL5156120 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAMAPTMAPK1TDP1 | |
| SCHEMBL5149817 | 0.82 | KMT2A (0.65) | SMN1; SMN2GAAMAPTMAPK1TDP1 | |
| SCHEMBL746991 | 0.73 | KMT2A (0.51) | SMN1; SMN2GAAMAPTMAPK1TDP1 | |
| SCHEMBL9778888 | 0.67 | APP (0.55) | SMN1; SMN2MAPTTDP1ALDH1A1HSD17B10 | |
| SCHEMBL5151489 | 0.66 | SMN1; SMN2 (0.80) | SMN1; SMN2GAAMAPTMAPK1TDP1 | |
| SCHEMBL5398622 | 0.66 | NPSR1 (0.50) | ALDH1A1LMNAMEN1KMT2AKCNA5 | |
| SCHEMBL16209660 | 0.66 | KMT2A (0.78) | SMN1; SMN2GAAMAPTMAPK1TDP1 | |
| SCHEMBL5402951 | 0.66 | CYP19A1 (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5151451 | 0.65 | SMN1; SMN2 (0.85) | SMN1; SMN2GAAMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017965-A1 | 1,3-THIAZOLIN-4-ONES AS THERAPEUTIC COMPOUNDS IN THE TREATMENT OF PAIN | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |