Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 5/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL2174363 | 0.87 | — | — | |
| Chloromethane SCHEMBL7131444 | 0.87 | — | — | |
| SCHEMBL156659 | 0.87 | FFAR3 (0.47) | TET2GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL17865 | 0.87 | — | — | |
| Carbamic Acid SCHEMBL28143284 | 0.84 | GRIK1 (0.41) | TET2GRIK1GRIK2GRM1GRM2 | |
| Ethylamine SCHEMBL2049220 | 0.84 | GRIK1 (0.41) | TET2GRIK1GRIK2GRM1GRM2 | |
| Ammonia Solution, Strong SCHEMBL93844 | 0.84 | — | — | |
| Oxalic Acid SCHEMBL7521918 | 0.84 | FFAR3 (0.44) | TET2GRIK1GRIK2GRM1GRM2 | |
| Methyl Alcohol SCHEMBL8845851 | 0.84 | — | — | |
| SCHEMBL5671506 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463349-B1 | Fluorinated acrylic polymer compositions as fluid loss additives in drilling fluids | 3M INNOVATIVE PROPERTIES CO (US) | 2014-06-18 | — | — | EP | disclosed |
| EP-2463349-A1 | Fluorinated acrylic polymer compositions as fluid loss additives in drilling fluids | 3M Innovative Properties Co. (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20030176568-A1 | High-solids coating composition | KANSAI PAINT CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| US-5395659-A | Cationic polymers, clear coats, automobiles | HERBERTS GMBH (DE) | 1995-03-07 | — | — | US | disclosed |