Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119199 | 0.89 | MAOB (0.56) | MAOBADORA3MAOAKDM4EKMT2A | |
| SCHEMBL7117863 | 0.81 | KDM4E (0.60) | MAOBKDM4EKMT2A | |
| SCHEMBL23332350 | 0.78 | MAOB (0.68) | MAOBADORA3MAOACA1CA2 | |
| SCHEMBL7114418 | 0.75 | ESR2 (0.55) | MAOBADORA3MAOAKDM4EKMT2A | |
| SCHEMBL13857249 | 0.74 | MAOB (0.69) | MAOBKDM4EKMT2ACA1CA2 | |
| SCHEMBL7123294 | 0.74 | MIF (0.72) | MAOBKDM4EKMT2A | |
| SCHEMBL7123865 | 0.74 | NPC1 (0.60) | MAOBMAOAKDM4EKMT2ACA1 | |
| SCHEMBL28585966 | 0.72 | MAOB (1.00) | MAOBADORA3MAOA | |
| SCHEMBL7169838 | 0.72 | MAPT (0.49) | MAOBADORA3MAOACA1CA2 | |
| SCHEMBL17857216 | 0.71 | MAOB (0.63) | MAOBADORA3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |