Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.57 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115695 | 0.85 | RXFP1 (0.64) | RXFP1ABCC1ABCG2HDAC6ALDH1A1 | |
| SCHEMBL7119641 | 0.76 | HTT (0.71) | RXFP1ABCC1ABCG2HDAC6ALDH1A1 | |
| SCHEMBL7115705 | 0.76 | HTT (0.71) | RXFP1ABCC1ABCG2HDAC6ALDH1A1 | |
| SCHEMBL7128300 | 0.74 | HTT (0.73) | RXFP1ABCC1ABCG2HDAC6ALDH1A1 | |
| SCHEMBL18292476 | 0.73 | RXFP1 (1.00) | RXFP1ABCC1ABCG2ALDH1A1TSHR | |
| SCHEMBL6922257 | 0.73 | RXFP1 (0.72) | RXFP1ABCC1ABCG2ALDH1A1TSHR | |
| SCHEMBL859357 | 0.71 | RXFP1 (0.70) | RXFP1ABCC1ABCG2ALDH1A1TSHR | |
| SCHEMBL6920444 | 0.71 | HTT (0.97) | RXFP1ABCC1ABCG2HDAC6ALDH1A1 | |
| SCHEMBL7118898 | 0.71 | HTT (0.97) | RXFP1ABCC1ABCG2HDAC6ALDH1A1 | |
| SCHEMBL6917425 | 0.71 | ABCC1 (1.00) | RXFP1ABCC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | RXFP1 354/4885ABCC1 1351/4885ABCG2 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.