Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156789 | 0.80 | TSHR (0.34) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL21153092 | 0.80 | TDP1 (0.42) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL1112988 | 0.78 | CYP3A4 (0.37) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL2639414 | 0.77 | TDP1 (0.46) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL4418163 | 0.76 | CYP3A4 (0.36) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL11441476 | 0.76 | CYP3A4 (0.36) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL10012964 | 0.75 | CYP3A4 (0.38) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL9928 | 0.75 | CYP3A4 (0.48) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL1396063 | 0.73 | TSHR (0.39) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| Ethylene SCHEMBL3010758 | 0.73 | CYP3A4 (0.46) | MAPTCACNA1BAPBA1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830336-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | CROMPTON CORP (US) | 2003-05-21 | — | — | EP | claimed |
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | claimed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5563288-A | REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE | OSI SPECIALTIES, INC. (US) | 1996-10-08 | — | — | US | claimed |
| EP-0830336-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | CROMPTON CORP (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-0830336-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | CROMPTON CORP (US) | 2003-05-21 | — | — | EP | disclosed |
| CN-1076338-C | Process for preparation of tertiary aminocarbonates and aminoethers | OSI SPECIALTIES INC (US) | 2001-12-19 | — | — | CN | disclosed |
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | disclosed |
| CN-1190387-A | Process for preparation of tertiary aminocarbonates and aminoethers | OSI SPECIALTIES INC (US) | 1998-08-12 | — | — | CN | disclosed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5563288-A | REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE | OSI SPECIALTIES, INC. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5563288-A | REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE | OSI SPECIALTIES, INC. (US) | 1996-10-08 | — | — | US | disclosed |