SCHEMBL7125722

SCHEMBL7125722

N#Cc1cccc(Oc2ccccc2N)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPT P10636 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
GAA P10253 4/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 1/20 0.40
RCE1 Q9Y256 1/20 0.39
ADRA2B P18089 1/20 0.38
PTGS1 P23219 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PLAU P00749 1/20 0.36
MAP4K4 O95819 1/20 0.36
HIF1A Q16665 1/20 0.36
TLR4 O00206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30487034 1.00 SMN1; SMN2 (0.45) SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL10717036 0.91 KDM4E (0.48) SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL8626899 0.87 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL9123978 0.87 SMN1; SMN2 (0.49) SMN1; SMN2KDM4ECYP2C9MAPTGAA
SCHEMBL29387985 0.87 SMN1; SMN2 (0.49) SMN1; SMN2KDM4ECYP2C9MAPTGAA
SCHEMBL9131619 0.85 GAA (0.53) SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL8465664 0.83 KDM4E (0.50) SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL27714118 0.80 KDM4E (0.37) SMN1; SMN2KDM4EMAPTCRHBPCRHR2
SCHEMBL21142943 0.79 AR (0.48) SMN1; SMN2KDM4ECYP3A4MAPTGAA
SCHEMBL28408790 0.79 POLB (0.51) SMN1; SMN2KDM4ECYP2C9MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058688-A Phthalonitrile containing phenolphthalein structural imide chain segment, preparation method thereof, prepolymer and cured product 中国石油天然气股份有限公司 2025-05-30 CN claimed
CN-120058687-A Phthalonitrile containing phenolphthalein structural imide chain segment, preparation method thereof, prepolymer and cured product 中国石油天然气股份有限公司 2025-05-30 CN claimed
WO-2025050464-A1 PREPARATION METHOD FOR BASALT FIBER-REINFORCED FIREPROOF AND FLAME-RETARDANT POLYMER-BASED COMPOSITE MATERIAL 电子科技大学长三角研究院(湖州) 2025-03-13 WO claimed
CN-117384111-A Preparation method of basalt fiber reinforced fireproof flame-retardant polymer matrix composite material 电子科技大学长三角研究院(湖州) 2024-01-12 CN claimed
CN-115650879-A Amino phenoxy phthalonitrile resin, polymer and preparation method thereof 电子科技大学 2023-01-31 CN claimed
CN-109694476-B Method for preparing ureido-containing autocatalytic poly (phthalonitrile) resin 河北工业大学 2021-04-13 CN claimed
CN-109096488-B Phthalonitrile resin composition and preparation method thereof 中国人民解放军国防科学技术大学 2021-02-26 CN claimed
CN-109096753-B Nitrile resin composite material and preparation method thereof 中国人民解放军国防科学技术大学 2021-02-23 CN claimed
CN-109705072-B Phthalonitrile oligomer, condensate thereof, and preparation method and application thereof 中国科学院化学研究所 2020-08-21 CN claimed
CN-120058688-A Phthalonitrile containing phenolphthalein structural imide chain segment, preparation method thereof, prepolymer and cured product 中国石油天然气股份有限公司 2025-05-30 CN disclosed
CN-120058687-A Phthalonitrile containing phenolphthalein structural imide chain segment, preparation method thereof, prepolymer and cured product 中国石油天然气股份有限公司 2025-05-30 CN disclosed
WO-2025050464-A1 PREPARATION METHOD FOR BASALT FIBER-REINFORCED FIREPROOF AND FLAME-RETARDANT POLYMER-BASED COMPOSITE MATERIAL 电子科技大学长三角研究院(湖州) 2025-03-13 WO disclosed
CN-117384111-A Preparation method of basalt fiber reinforced fireproof flame-retardant polymer matrix composite material 电子科技大学长三角研究院(湖州) 2024-01-12 CN disclosed
CN-113939557-B Curable fluoropolymer compositions comprising phthalonitrile and nucleophilic functional group containing compounds and cured articles made therefrom 3M创新有限公司 2023-08-18 CN disclosed
US-6590118-B1 Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) NOVO NORDISK A/S (DK) 2003-07-08 US disclosed
EP-1220832-A1 NOVEL AROMATIC COMPOUNDS NOVO NORDISK A/S (DK) 2002-07-10 EP disclosed
WO-2001023347-A1 NOVEL AROMATIC COMPOUNDS NOVO NORDISK A/S (DK) 2001-04-05 WO disclosed
US-5292854-A Synthesis of phthalonitrile resins containing ether and imide linkages with aromatic diamine curing agent THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-03-08 US disclosed
US-5159054-A Synthesis of phthalonitrile resins containing ether and imide linkages THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1992-10-27 US disclosed
US-5003078-A Synthesis of phthalonitrile resins containing ether and imide linkages THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-03-26 US disclosed