Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126083 | 0.86 | AKR1B1 (0.60) | AKR1B1 | |
| SCHEMBL6207608 | 0.80 | AKR1B1 (0.91) | AKR1B1 | |
| SCHEMBL6206594 | 0.80 | AKR1B1 (0.81) | AKR1B1 | |
| SCHEMBL6205476 | 0.78 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6206457 | 0.78 | AKR1B1 (0.74) | AKR1B1 | |
| SCHEMBL6206866 | 0.77 | AKR1B1 (0.75) | AKR1B1 | |
| SCHEMBL7295107 | 0.76 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6207081 | 0.76 | AKR1B1 (0.91) | AKR1B1 | |
| SCHEMBL6897167 | 0.73 | AKR1B1 (0.54) | AKR1B1 | |
| SCHEMBL6206599 | 0.73 | AKR1B1 (1.00) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392310-A1 | COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | Pfizer Products Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002087584-A1 | COMBINATIONS OF ALDOSE REDUCTASE INHIBITORS AND CYCLOOXYGENASE-2 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-11-07 | — | — | WO | disclosed |