Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818724 | 0.89 | PDE10A (0.34) | PDE10AF10ALDH1A1PKMABCB1 | |
| SCHEMBL6818693 | 0.86 | ALB (0.36) | PDE10AF10ALDH1A1PKMABCB1 | |
| SCHEMBL7129786 | 0.86 | ALB (0.42) | PDE10AF10DYRK1AALDH1A1PKM | |
| SCHEMBL6818372 | 0.85 | F10 (0.34) | PDE10AF10ALDH1A1PKMABCB1 | |
| SCHEMBL6818784 | 0.84 | PDE10A (0.34) | PDE10AF10ALDH1A1PKMABCB1 | |
| SCHEMBL6819112 | 0.81 | ABCB1 (0.33) | PDE10AF10SCN9AALDH1A1PKM | |
| SCHEMBL6833230 | 0.74 | HIF1A (0.37) | PDE10AALDH1A1PKMNR1H4 | |
| SCHEMBL6815114 | 0.74 | HIF1A (0.37) | PDE10ACETPALDH1A1LRRK2 | |
| SCHEMBL6822117 | 0.74 | HIF1A (0.37) | PDE10ACETPALDH1A1PKMALB | |
| SCHEMBL6814346 | 0.74 | ALB (0.42) | ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |